TXNL4A Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the U5 small ribonucleoprotein particle (snRNP), and is involved in pre-mRNA splicing. This protein contains a thioredoxin-like fold and it is expected to interact with multiple proteins. Protein-protein interactions have been observed with the polyglutamine tract-binding protein 1 (PQBP1) . Mutations in both the coding region and promoter region of this gene have been associated with Burn-McKeown syndrome, which is a rare disorder characterized by craniofacial dysmorphisms, cardiac defects, hearing loss, and bilateral choanal atresia. A pseudogene of this gene is found on chromosome 2. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
10907
Swiss Prot
P83876
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-142 of human TXNL4A (NP_006692.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cell Cycle
Purification
Affinity purification
Positive Control
LO2
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=13-451
Calculated Molecular Weight
Observed: 13kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
TXNL4A
Positive Control 2
HeLa
Positive Control 3
Jurkat
Positive Control 4
HL-60
Positive Control 5
Mouse pancreas
Positive Control 6
Mouse kidney
NCBI Official Name
Thioredoxin like 4A
NCBI Organism
Homo sapiens
Other Product Names
BMKS, DIB1, DIM1, SNRNP15, TXNL4, U5-15kD, thioredoxin-like protein 4A, DIM1 protein homolog, spliceosomal U5 snRNP-specific 15 kDa protein, thioredoxin-like 4, thioredoxin-like U5 snRNP protein U5-15kD
Tested Applications
WB
Physical Properties
Liquid
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