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CYP4F2 Antibody

Product Specifications

Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. The enzyme starts the process of inactivating and degrading leukotriene B4, a potent mediator of inflammation. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F11, is approximately 16 kb away.

NCBI Gene ID

8529

Swiss Prot

P78329

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 40-120 of human CYP4F2 (NP_001073.3) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Immunology, Innate Immunity, Signal Transduction

Purification

Affinity purification

Positive Control

LO2

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 60kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

CYP4F2

Positive Control 2

HepG2

Positive Control 3

293T

NCBI Official Name

Cytochrome P450 family 4 subfamily F member 2

NCBI Organism

Homo sapiens

Other Product Names

CPF2, phylloquinone omega-hydroxylase CYP4F2, 20-HETE synthase, 20-hydroxyeicosatetraenoic acid synthase, CYPIVF2, arachidonic acid omega-hydroxylase, cytochrome P450 4F2, cytochrome P45family 4, subfamily F, polypeptide 2, cytochrome P45subfamily IVF, polypeptide 2, cytochrome P450-LTB-omega, leukotriene-B (4) 20-monooxygenase 1, leukotriene-B (4) omega-hydroxylase 1

Tested Applications

WB

Physical Properties

Liquid

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