PRKAR1B Antibody

Product Specifications

Background

The protein encoded by this gene is a regulatory subunit of cyclic AMP-dependent protein kinase A (PKA), which is involved in the signaling pathway of the second messenger cAMP. Two regulatory and two catalytic subunits form the PKA holoenzyme, disbands after cAMP binding. The holoenzyme is involved in many cellular events, including ion transport, metabolism, and transcription. Several transcript variants encoding the same protein have been found for this gene.

NCBI Gene ID

5575

Swiss Prot

P31321

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 190-290 of human PRKAR1B (NP_002726.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cancer, Cell Cycle, Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

U-251MG

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 43kDa

Fragment

IgG

Applications Notes

WB: 1:1000 - 1:4000

Symbol

PRKAR1B

Positive Control 2

HeLa

Positive Control 3

Jurkat

Positive Control 4

HepG2

Positive Control 5

BT-474

Positive Control 6

Mouse brain

NCBI Official Name

CAMP-dependent protein kinase type I-beta regulatory subunit

NCBI Organism

Homo sapiens

Other Product Names

CAMP-dependent protein kinase type I-beta regulatory subunit, PRKAR1B

Tested Applications

Physical Properties

Liquid

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