INPPL1 Antibody

Product Specifications

Background

The protein encoded by this gene is an SH2-containing 5'-inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling. Additionally, this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer.

NCBI Gene ID

3636

Swiss Prot

O15357

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 100-310 of human INPPL1 (NP_001558.3) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Growth Factors, Immunology, Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

HeLa

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 160kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

INPPL1

Positive Control 2

U-251MG

Positive Control 3

A-549

Positive Control 4

BT-474

Positive Control 5

Mouse heart

Positive Control 6

Mouse brain

NCBI Official Name

Inositol polyphosphate phosphatase like 1

NCBI Organism

Homo sapiens

Other Product Names

OPSMD, SHIP2, phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2, 51C protein, INPPL-1, SH2 domain-containing inositol-5'-phosphatase 2, SHIP-2, protein 51C