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PCDH15 Antibody

Product Specifications

Background

This gene is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene result in hearing loss and Usher Syndrome Type IF (USH1F) . Extensive alternative splicing resulting in multiple isoforms has been observed in the mouse ortholog. Similar alternatively spliced transcripts are inferred to occur in human, and additional variants are likely to occur.

NCBI Gene ID

65217

Swiss Prot

Q96QU1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 160-400 of human PCDH15 (NP_001136235.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Affinity purification

Positive Control

SH-SY5Y

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 100kDa

Fragment

IgG

Symbol

PCDH15

Positive Control 2

293T

Positive Control 3

A-549

Positive Control 4

Raji

Positive Control 5

Mouse brain

Positive Control 6

Mouse liver

NCBI Official Name

Protocadherin-related 15

NCBI Organism

Homo sapiens

Other Product Names

PCDH15, RP11-449J3.2, DFNB23, DKFZp667A1711, USH1F, CDHR15

Tested Applications

WB, IHC

Physical Properties

Liquid

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