DAG1 Antibody

Product Specifications

Background

This gene encodes dystroglycan, a central component of dystrophin-glycoprotein complex that links the extracellular matrix and the cytoskeleton in the skeletal muscle. The encoded preproprotein undergoes O- and N-glycosylation, and proteolytic processing to generate alpha and beta subunits. Certain mutations in this gene are known to cause distinct forms of muscular dystrophy. Alternative splicing results in multiple transcript variants, all encoding the same protein.

NCBI Gene ID

1605

Swiss Prot

Q14118

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 654-749 of human DAG1 (NP_004384.4) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

HepG2

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 43kDa/95kDa

Fragment

IgG

Symbol

DAG1

Positive Control 2

U2OS

Positive Control 3

SW480

Positive Control 4

HeLa

Positive Control 5

Mouse skeletal muscle

Positive Control 6

Mouse lung

NCBI Official Name

Dystroglycan 1 (dystrophin-associated glycoprotein 1)

NCBI Organism

Homo sapiens

Other Product Names

DAG1, dystroglycan 1 (dystrophin-associated glycoprotein 1), dystroglycan 1, DAG, beta-dystroglycan, alpha-dystroglycan, AGRNR, A3a, 156DAG, MDDGC7, MDDGC9