TRPM7 Antibody

Product Specifications

Background

The protein encoded by this gene is both an ion channel and a serine/threonine protein kinase. The kinase activity is essential for the ion channel function, which serves to increase intracellular calcium levels and to help regulate magnesium ion homeostasis. Defects in this gene are a cause of amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam. Alternative splicing of this gene results in multiple transcript variants.

NCBI Gene ID

54822

Swiss Prot

Q96QT4

Host

Rabbit

Reactivity

Mouse

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 756-855 of human TRPM7 (NP_060142.3) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

Mouse skeletal muscle

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 230kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

TRPM7

NCBI Official Name

Transient receptor potential cation channel, subfamily M, member 7

NCBI Organism

Homo sapiens

Other Product Names

TRPM7, transient receptor potential cation channel, subfamily M, member 7, CHAK, CHAK1, LTRPC7, FLJ20117, TRP-PLIK, LTRPC ion channel family member 7, homolog of mouse transient receptor potential-phospholipase C-interacting kinase CHaK hypothetical protein FLJ20117