ROBO2 Antibody

Product Specifications

Background

The protein encoded by this gene belongs to the ROBO family, part of the immunoglobulin superfamily of proteins that are highly conserved from fly to human. The encoded protein is a transmembrane receptor for the slit homolog 2 protein and functions in axon guidance and cell migration. Mutations in this gene are associated with vesicoureteral reflux, characterized by the backward flow of urine from the bladder into the ureters or the kidney. Alternative splicing results in multiple transcript variants.

NCBI Gene ID

6092

Swiss Prot

Q9HCK4

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 450-660 of human ROBO2 (NP_001122401.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

Affinity purification

Positive Control

SH-SY5Y

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 175kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

ROBO2

Positive Control 2

SKOV3

Positive Control 3

A-549

Positive Control 4

Mouse brain

Positive Control 5

Mouse lung

Positive Control 6

Rat brain

NCBI Official Name

Roundabout, axon guidance receptor, homolog 2 (Drosophila)

NCBI Organism

Homo sapiens

Other Product Names

ROBO2, KIAA1568, SAX3

Tested Applications

Physical Properties

Liquid

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