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FZD3 Antibody

Product Specifications

Background

This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development. Alternative splicing results in multiple transcript variants. This gene is a susceptibility locus for schizophrenia.

NCBI Gene ID

7976

Swiss Prot

Q9NPG1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 23-205 of human FZD3 (NP_059108.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction, Stem Cell

Purification

Affinity purification

Positive Control

SH-SY5Y

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 76kDa

Fragment

IgG

Symbol

FZD3

Positive Control 2

HeLa

Positive Control 3

MCF7

Positive Control 4

Mouse brain

Positive Control 5

Mouse kidney

NCBI Official Name

Frizzled class receptor 3

NCBI Organism

Homo sapiens

Other Product Names

FZD3, frizzled homolog 3 (Drosophila), Fz-3, hFz3, frizzled 3

Tested Applications

WB, IHC

Physical Properties

Liquid

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