CHRNE Antibody
Product Specifications
Background
Acetylcholine receptors at mature mammalian neuromuscular junctions are pentameric protein complexes composed of four subunits in the ratio of two alpha subunits to one beta, one epsilon, and one delta subunit. The acetylcholine receptor changes subunit composition shortly after birth when the epsilon subunit replaces the gamma subunit seen in embryonic receptors. Mutations in the epsilon subunit are associated with congenital myasthenic syndrome.
NCBI Gene ID
1145
Swiss Prot
Q04844
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 21-239 of human CHRNE (NP_000071.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
Affinity purification
Positive Control
HepG2
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 45kDa
Fragment
IgG
Applications Notes
WB: 1:1000 - 1:4000
Symbol
CHRNE
Positive Control 2
Mouse skeletal muscle
Positive Control 3
Rat kidney
Positive Control 4
Rat skeletal muscle
NCBI Official Name
Cholinergic receptor, nicotinic, epsilon (muscle)
NCBI Organism
Homo sapiens
Other Product Names
CHRNE, ACHRE, CMS1D, CMS1E, CMS2A, FCCMS, SCCMS
Tested Applications
WB
Physical Properties
Liquid
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