YAP1 Antibody, KO Validated
Product Specifications
Background
This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.
NCBI Gene ID
10413
Swiss Prot
P46937
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 155-504 of human YAP1 (NP_001123617.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Validation
Antibody is Knockout validated.
Field of Research
Cancer, Cell Cycle, Signal Transduction, Transcription
Purification
Affinity purification
Positive Control
HeLa
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 72kDa
Fragment
IgG
Symbol
YAP1
Positive Control 2
LO2
Positive Control 3
BT-474
Positive Control 4
A549
NCBI Official Name
Yes-associated protein 1
NCBI Organism
Homo sapiens
Other Product Names
YAP1, YAP, YAP2, YAP65, YKI
Tested Applications
WB, IHC, IF, IP
Physical Properties
Liquid
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