PPIA Antibody
Product Specifications
Background
This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The encoded protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported.
NCBI Gene ID
5478
Swiss Prot
P62937
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-165 of human PPIA (NP_066953.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
K-562
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 17kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
PPIA
Positive Control 2
Jurkat
Positive Control 3
HepG2
Positive Control 4
HeLa
Positive Control 5
NIH/3T3
Positive Control 6
Mouse lung
NCBI Official Name
Peptidylprolyl isomerase A (cyclophilin A)
NCBI Organism
Homo sapiens
Other Product Names
PPIA, CYPA, CYPH, MGC117158, MGC12404, MGC23397, HEL-S-69p
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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