SNAP25 Antibody
Product Specifications
Background
Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs) . The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene.
NCBI Gene ID
6616
Swiss Prot
P60880
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-206 of human SNAP25 (NP_003072.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
HeLa
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=13-354
Calculated Molecular Weight
Observed: 30kDa
Fragment
IgG
Symbol
SNAP25
Positive Control 2
SH-SY5Y
Positive Control 3
PC-12
NCBI Official Name
Synaptosomal-associated protein, 25kDa
NCBI Organism
Homo sapiens
Other Product Names
SNAP25, synaptosomal-associated protein, 25 kDa, HGNC:11132, FLJ23079, SNAP, SNAP-25, bA416N4.2, dJ1068F16.2, synaptosomal-associated protein 25
Tested Applications
WB, IF
Physical Properties
Liquid
Curated Selection
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