PI3 Kinase p110 beta Antibody
Product Specifications
Background
This gene encodes an isoform of the catalytic subunit of phosphoinositide 3-kinase (PI3K) . These kinases are important in signaling pathways involving receptors on the outer membrane of eukaryotic cells and are named for their catalytic subunit. The encoded protein is the catalytic subunit for PI3Kbeta (PI3KB) . PI3KB has been shown to be part of the activation pathway in neutrophils which have bound immune complexes at sites of injury or infection. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
5291
Swiss Prot
P42338
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 771-1070 of human PI3 Kinase p110 beta (NP_006210.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cell Cycle, Immunology, Innate Immunity, Signal Transduction
Purification
Affinity purification
Positive Control
DU145
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 122kDa
Fragment
IgG
Symbol
PIK3CB
Positive Control 2
SW480
Positive Control 3
HeLa
Positive Control 4
Mouse lung
NCBI Official Name
Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
NCBI Organism
Homo sapiens
Other Product Names
PIK3CB, PI3K, PIK3C1, P110BETA, PI3KBETA
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Curated Selection
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