MARCKS Antibody
Product Specifications
Background
The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.
NCBI Gene ID
4082
Swiss Prot
P29966
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MARCKS (NP_002347.5) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
Rat brain
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 80kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
MARCKS
NCBI Official Name
Myristoylated alanine-rich protein kinase C substrate
NCBI Organism
Homo sapiens
Other Product Names
MARCKS, 80K-L, 80K-L protein, MACS, MRACKS, Phosphomyristin, PKCSL, PRKCSL
Tested Applications
WB
Physical Properties
Liquid
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