SLC1A2 Antibody

Product Specifications

Background

This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Improper regulation of this gene is thought to be associated with several neurological disorders. Alternatively spliced transcript variants of this gene have been identified.

NCBI Gene ID

6506

Swiss Prot

P43004

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 495-574 of human SLC1A2 (NP_004162.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

MCF7

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 65kDa

Fragment

IgG

Symbol

SLC1A2

Positive Control 2

HepG2

Positive Control 3

SW480

Positive Control 4

Mouse liver

Positive Control 5

Rat liver

NCBI Official Name

Solute carrier family 1 member 2

NCBI Organism

Homo sapiens

Other Product Names

EAAT2, EIEE41, GLT-1, HBGT, excitatory amino acid transporter 2, excitotoxic amino acid transporter 2, glutamate/aspartate transporter II, sodium-dependent glutamate/aspartate transporter 2, solute carrier family 1 (glial high affinity glutamate transporter), member 2