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NUR77 Antibody

Product Specifications

Background

This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

3164

Swiss Prot

P22736

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human NUR77 (NP_775180.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cancer, Cell Cycle, Immunology, Signal Transduction, Transcription

Purification

Affinity purification

Positive Control

SH-SY5Y

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 71kDa

Fragment

IgG

Symbol

NR4A1

NCBI Official Name

Nuclear receptor subfamily 4, group A, member 1

NCBI Organism

Homo sapiens

Other Product Names

NR4A1, HMR, N10, TR3, NP10, GFRP1, NAK-1, NGFIB, NUR77

Tested Applications

WB, IF

Physical Properties

Liquid

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