BIRC3 Antibody

Product Specifications

Background

This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified.

NCBI Gene ID

330

Swiss Prot

Q13489

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human BIRC3 (NP_001156.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cancer, Cell Cycle, Immunology

Purification

Affinity purification

Positive Control

U-937

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 68kDa

Fragment

IgG

Symbol

BIRC3

NCBI Official Name

Baculoviral IAP repeat containing 3

NCBI Organism

Homo sapiens

Other Product Names

BIRC3, TNFR2-TRAF signaling complex protein, RNF49, MIHC, MALT2, HIAP1, HAIP1, c-IAP2, CIAP2, baculoviral IAP repeat-containing protein 3, baculoviral IAP repeat-containing 3, apoptosis inhibitor 2, API2, AIP1, IAP1