TGFBR1 Antibody

Product Specifications

Background

The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS) . Multiple transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

7046

Swiss Prot

P36897

Host

Rabbit

Reactivity

Human, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 34-124 of human TGFBR1 (NP_001124388.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Growth Factors, Signal Transduction, Stem Cell

Purification

Affinity purification

Positive Control

HepG2

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 56kDa

Fragment

IgG

Symbol

TGFBR1

Positive Control 2

HeLa

Positive Control 3

PC-3

NCBI Official Name

Transforming growth factor, beta receptor 1

NCBI Organism

Homo sapiens

Other Product Names

Activin A receptor type II-like kinase, 53kD, TGF-beta type I receptor, TGF-beta receptor type-1, TGF-beta receptor type I, TGFR-1, SKR4, LDS2A, LDS1A, ALK5, ALK-5, ACVRLK4, AAT5, transforming growth factor, beta receptor 1, TGFBR1, transforming growth factor-beta receptor type I, beta receptor I (activin A receptor type II-like kinase, 53kD), transforming growth factor beta receptor I, tbetaR-I, serine/threonine-protein kinase receptor R4, activin receptor-like kinase 5, activin A receptor type II-like kinase, 53kDa