EZR Antibody
Product Specifications
Background
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.
NCBI Gene ID
7430
Swiss Prot
P15311
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 350-470 of human EZR (NP_003370.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Immunology, Signal Transduction
Purification
Affinity purification
Positive Control
M21
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 90kDa
Fragment
IgG
Symbol
EZR
Positive Control 2
SW480
Positive Control 3
U-251MG
Positive Control 4
293T
Positive Control 5
Mouse intestine
Positive Control 6
Mouse brain
NCBI Official Name
Ezrin
NCBI Organism
Homo sapiens
Other Product Names
Ezrin, VIL2, villin 2 (ezrin), CVIL, CVL, DKFZp762H157, FLJ26216, MGC1584, cytovillin, ezrin, villin 2
Tested Applications
WB, IHC, IF, IP
Physical Properties
Liquid
Curated Selection
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