IL17A Antibody
Product Specifications
Background
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO) . High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
NCBI Gene ID
3605
Swiss Prot
Q16552
Host
Rabbit
Reactivity
Human, Mouse, Rat, Monkey
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 24-155 of human IL17A (NP_002181.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cancer, Cell Cycle, Chemokines & Cytokines, Immunology, Innate Immunity
Purification
Affinity purification
Positive Control
Mouse liver
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 17kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
IL17A
Positive Control 2
Rat liver
NCBI Official Name
Interleukin 17A
NCBI Organism
Homo sapiens
Other Product Names
Interleukin-17A; CTLA-8; Cytotoxic T Lymphocyte-associated Antigen 8
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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