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SMNDC1 Antibody

Product Specifications

Background

This gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. The protein encoded by this gene is a nuclear protein that has been identified as a constituent of the spliceosome complex. This gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene.

NCBI Gene ID

10285

Swiss Prot

O75940

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-238 of human SMNDC1 (NP_005862.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cell Cycle

Purification

Affinity purification

Positive Control

HeLa

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 27kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

SMNDC1

Positive Control 2

Jurkat

Positive Control 3

HT-1080

Positive Control 4

PC-12

Positive Control 5

SH-SY5Y

Positive Control 6

SKOV3

NCBI Official Name

Survival motor neuron domain containing 1

NCBI Organism

Homo sapiens

Other Product Names

SMNDC1, SMNR, SPF30, TDRD16C

Tested Applications

WB

Physical Properties

Liquid

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