CDC73 Antibody
Product Specifications
Background
This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.
NCBI Gene ID
79577
Swiss Prot
Q6P1J9
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A synthetic peptide of human CDC73
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
Affinity purification
Positive Control
Mouse testis
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 61kDa
Fragment
IgG
Symbol
CDC73
NCBI Official Name
Parafibromin
NCBI Organism
Homo sapiens
Other Product Names
Parafibromin, Cell division cycle protein 73 homolog, Hyperparathyroidism 2 protein, CDC73, C1orf28, HRPT2
Tested Applications
WB, IHC, IF, Flow
Physical Properties
Liquid
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