TGFBR3 Antibody
Product Specifications
Background
This locus encodes the transforming growth factor (TGF) -beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
NCBI Gene ID
7049
Swiss Prot
Q03167
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 140-340 of human TGFBR3 (NP_003234.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Chemokines & Cytokines, Immunology, Innate Immunity, Signal Transduction, Stem Cell
Purification
Affinity purification
Positive Control
SH-SY5Y
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 110kDa
Fragment
IgG
Symbol
TGFBR3
Positive Control 2
Mouse brain
Positive Control 3
Mouse lung
Positive Control 4
Rat brain
NCBI Official Name
Transforming growth factor, beta receptor III
NCBI Organism
Homo sapiens
Other Product Names
TGFBR3, transforming growth factor, beta receptor III, BGCAN, betaglycan, betaglycan proteoglycan
Tested Applications
WB, IF
Physical Properties
Liquid
Curated Selection
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