TJP2 Antibody
Product Specifications
Background
This gene encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in this gene have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal dominant deafness-51. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.
NCBI Gene ID
9414
Swiss Prot
Q9UDY2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 951-1190 of human TJP2 (NP_004808.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
HeLa
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 160kDa
Fragment
IgG
Symbol
TJP2
Positive Control 2
HepG2
Positive Control 3
Jurkat
Positive Control 4
Mouse pancreas
NCBI Official Name
Tight junction protein 2
NCBI Organism
Homo sapiens
Other Product Names
TJP2, MGC26306, X104, ZO-2, ZO2, DFNA51, DUP9q21.11, C9DUPq21.11
Tested Applications
WB, IHC
Physical Properties
Liquid
Curated Selection
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