SMAD6 Antibody
Product Specifications
Background
The protein encoded by this gene belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling. Multiple transcript variants have been found for this gene.
NCBI Gene ID
4091
Swiss Prot
O43541
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 257-496 of human SMAD6 (NP_005576.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction, Stem Cell, Transcription
Purification
Affinity purification
Positive Control
22Rv1
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 48kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:1000
Symbol
SMAD6
Positive Control 2
Mouse heart
Positive Control 3
Rat brain
NCBI Official Name
SMAD family member 6
NCBI Organism
Homo sapiens
Other Product Names
SMAD6, AOVD2, MADH6, MADH7, HsT17432
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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