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SOX2 Antibody

Product Specifications

Background

This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT) .

NCBI Gene ID

6657

Swiss Prot

P48431

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human SOX2 (NP_003097.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Neuroscience, Signal Transduction, Stem Cell, Transcription

Purification

Affinity purification

Positive Control

MCF7

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=13-205

Calculated Molecular Weight

Observed: 39kDa

Fragment

IgG

Symbol

SOX2

Positive Control 2

293T

Positive Control 3

Mouse brain

Positive Control 4

Rat brain

NCBI Official Name

SRY (sex determining region Y) -box 2

NCBI Organism

Homo sapiens

Other Product Names

SOX2 Antibody: ANOP3, MCOPS3, Transcription factor SOX-2

Tested Applications

WB, IHC, IF, IP

Physical Properties

Liquid

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