SOX2 Antibody
Product Specifications
Background
This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT) .
NCBI Gene ID
6657
Swiss Prot
P48431
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human SOX2 (NP_003097.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Neuroscience, Signal Transduction, Stem Cell, Transcription
Purification
Affinity purification
Positive Control
MCF7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 39kDa
Fragment
IgG
Symbol
SOX2
Positive Control 2
293T
Positive Control 3
Mouse brain
Positive Control 4
Rat brain
NCBI Official Name
SRY (sex determining region Y) -box 2
NCBI Organism
Homo sapiens
Other Product Names
SOX2 Antibody: ANOP3, MCOPS3, Transcription factor SOX-2
Tested Applications
WB, IHC, IF, IP
Physical Properties
Liquid
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