MYCN Antibody
Product Specifications
Background
This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
4613
Swiss Prot
P04198
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 168-267 of human MYCN (NP_005369.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction, Transcription
Purification
Affinity purification
Positive Control
SH-SY5Y
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 49kDa
Fragment
IgG
Symbol
MYCN
Positive Control 2
Mouse heart
Positive Control 3
Rat brain
NCBI Official Name
V-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NCBI Organism
Homo sapiens
Other Product Names
MYCN, NMYC, ODED, MODED, N-myc, MYCNOT, bHLHe37
Tested Applications
WB, IHC
Physical Properties
Liquid
Curated Selection
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