IGFBP2 Antibody
Product Specifications
Background
The protein encoded by this gene is one of six similar proteins that bind insulin-like growth factors I and II (IGF-I and IGF-II) . The encoded protein can be secreted into the bloodstream, where it binds IGF-I and IGF-II with high affinity, or it can remain intracellular, interacting with many different ligands. High expression levels of this protein promote the growth of several types of tumors and may be predictive of the chances of recovery of the patient. Several transcript variants, one encoding a secreted isoform and the others encoding nonsecreted isoforms, have been found for this gene.
NCBI Gene ID
3485
Swiss Prot
P18065
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human IGFBP2 (NP_000588.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Growth Factors, Signal Transduction
Purification
Affinity purification
Positive Control
LO2
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 37kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
IGFBP2
Positive Control 2
HeLa
Positive Control 3
SW480
NCBI Official Name
Insulin-like growth factor binding protein 2, 36kDa
NCBI Organism
Homo sapiens
Other Product Names
IGFBP2, IBP2, IGF-BP53
Tested Applications
WB
Physical Properties
Liquid
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