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RARA Antibody

Product Specifications

Background

This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.

NCBI Gene ID

5914

Swiss Prot

P10276

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-457 of human RARA (NP_001019980.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction, Transcription

Purification

Affinity purification

Positive Control

HepG2

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 65kDa

Fragment

IgG

Symbol

RARA

Positive Control 2

Mouse testis

Positive Control 3

Rat testis

NCBI Official Name

Retinoic acid receptor, alpha

NCBI Organism

Homo sapiens

Other Product Names

RARA, RAR, NR1B1

Tested Applications

WB, IHC, IF

Physical Properties

Liquid

Curated Selection

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