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Vimentin Antibody

Product Specifications

Background

This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL) -derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.

NCBI Gene ID

7431

Swiss Prot

P08670

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human Vimentin

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Neuroscience, Signal Transduction, Stem Cell

Purification

Affinity purification

Positive Control

Jurkat

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 56kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

VIM

Positive Control 2

Raji

Positive Control 3

Mouse eye

Positive Control 4

Rat eye

NCBI Official Name

Vimentin

NCBI Organism

Homo sapiens

Other Product Names

Vimentin, VIM

Tested Applications

WB

Physical Properties

Liquid

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