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SOD1 Antibody

Product Specifications

Background

The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.

NCBI Gene ID

6647

Swiss Prot

P00441

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-154 of human SOD1 (NP_000445.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cancer, Cell Cycle, Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

HeLa

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 20kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

SOD1

Positive Control 2

MCF7

NCBI Official Name

Superoxide dismutase 1, soluble

NCBI Organism

Homo sapiens

Other Product Names

SOD1, ALS, ALS1, IPOA, SOD, homodimer, hSod1, HEL-S-44

Tested Applications

WB

Physical Properties

Liquid

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