HDAC1 Antibody, KO Validated
Product Specifications
Background
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
NCBI Gene ID
3065
Swiss Prot
Q13547
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 393-482 of human HDAC1 (NP_004955.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Validation
Antibody is Knockout validated.
Field of Research
Apoptosis, Cell Cycle, Immunology, Neuroscience, Signal Transduction, Stem Cell
Purification
Affinity purification
Positive Control
293T
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 62kDa
Fragment
IgG
Symbol
HDAC1
Positive Control 2
HeLa
Positive Control 3
HepG2
Positive Control 4
MCF7
Positive Control 5
Mouse thymus
Positive Control 6
Mouse testis
NCBI Official Name
Histone deacetylase 1
NCBI Organism
Homo sapiens
Other Product Names
HDAC1 Antibody: HD1, RPD3, GON-10, RPD3L1, Histone deacetylase 1, HD1
Tested Applications
WB, IHC, IF, IP
Physical Properties
Liquid
Curated Selection
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