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C-Fos Antibody

Product Specifications

Background

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.

NCBI Gene ID

2353

Swiss Prot

P01100

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 211-380 of human c-Fos (NP_005243.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Immunology, Neuroscience, Signal Transduction, Transcription

Purification

Affinity purification

Positive Control

Mouse spinal cord

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=13-096

Calculated Molecular Weight

Observed: 70kDa/62kDa

Fragment

IgG

Symbol

FOS

Positive Control 2

Mouse lung

Positive Control 3

Mouse brain

Positive Control 4

Mouse intestine

Positive Control 5

HepG2

NCBI Official Name

FBJ murine osteosarcoma viral oncogene homolog

NCBI Organism

Homo sapiens

Other Product Names

FOS, p55, AP-1, C-FOS

Tested Applications

WB, IHC, IF

Physical Properties

Liquid

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