TH Antibody
Product Specifications
Background
The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
NCBI Gene ID
7054
Swiss Prot
P07101
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TH (NP_954986.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
Mouse brain
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 59kDa
Fragment
IgG
Symbol
TH
Positive Control 2
Rat brain
NCBI Official Name
Tyrosine hydroxylase
NCBI Organism
Homo sapiens
Other Product Names
TH, tyrosine hydroxylase, HGNC:11782, TYH, DYT14, DYT5b, dystonia 14, tyrosine 3-monooxygenase
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
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