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Iscalimab (CD40/TNFRSF5) - Research Grade Biosimilar

Product Specifications

Background

Iscalimab (CFZ533) is fully human monoclonal antibody targeting differentiation cluster 40 (CD40), which cy pathway, preventing CD40 pathway signaling and CD40 + cell type activation It has become a new therapy for the treatment of solid organs and related autoimmune diseases.

Immunogen

Homo sapiens / CD40/TNFRSF5 [Homo sapiens]

Clonality

Recombinant Monoclonal

Conjugation

Unconjugated

Type

Primary Antibodies, Biosimilars

Source

CHO cells

Field of Research

Neuroscience

Purification

>95%

Concentration

Batch dependent

Buffer

PBS buffer pH7.5

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 ˚ C for 1-2 weeks. Store at -20 ˚ C for 12 months. Store at -80 ˚ C for long term storage.

Fragment

IgG1-kappa

NCBI Organism

Homo sapiens

Other Product Names

CFZ-533, NVP-CFZ533, OM11-62MF

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