Durvalumab (CD274/B7-H1/PDL1) - Research Grade Biosimilar

Product Specifications

Background

Durvalumab (MEDI 4736) is an humanized anti-PD-L1 monoclonal antibody, it fullyly blocks the binding of PD-L1 to both PD-1 and CD80, with IC50s of 0.1 and 0.04 nM, respectively. ()

Immunogen

Homo sapiens / CD274/B7-H1/PDL1 [Homo sapiens]

Clonality

Recombinant Monoclonal

Conjugation

Unconjugated

Type

Primary Antibodies, Biosimilars

Source

CHO cells

Field of Research

Cancer, Immunology

Purification

>95%

Concentration

Batch dependent

Buffer

PBS buffer pH7.5

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 ˚ C for 1-2 weeks. Store at -20 ˚ C for 12 months. Store at -80 ˚ C for long term storage.