Durvalumab (CD274/B7-H1/PDL1) - Research Grade Biosimilar
Product Specifications
Background
Durvalumab (MEDI 4736) is an humanized anti-PD-L1 monoclonal antibody, it fullyly blocks the binding of PD-L1 to both PD-1 and CD80, with IC50s of 0.1 and 0.04 nM, respectively. ()
Immunogen
Homo sapiens / CD274/B7-H1/PDL1 [Homo sapiens]
Clonality
Recombinant Monoclonal
Conjugation
Unconjugated
Type
Primary Antibodies, Biosimilars
Source
CHO cells
Field of Research
Cancer, Immunology
Purification
>95%
Concentration
Batch dependent
Buffer
PBS buffer pH7.5
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 ˚ C for 1-2 weeks. Store at -20 ˚ C for 12 months. Store at -80 ˚ C for long term storage.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=10-680
Fragment
IgG1-kappa
NCBI Organism
Homo sapiens
Other Product Names
MEDI4736
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