ALOX12B Antibody

Product Specifications

Background

This gene encodes an enzyme involved in the converstion of arachidonic acid to 12R-hydroxyeicosatetraenoic acid. Mutations in this gene are associated with nonbullous congenital ichthyosiform erythroderma.

NCBI Gene ID

242

Swiss Prot

O75342

Accession Number

O75342

Host

Rabbit

Reactivity

Human

Immunogen

This ALOX12B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 622-652 amino acids from the C-terminal region of human ALOX12B.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

80 kDa

Fragment

Rabbit Ig

Symbol

ALOX12B

NCBI Official Name

Arachidonate 12-lipoxygenase, 12R-type

NCBI Organism

Homo sapiens

Background Reference 01

Han, S., et al. Hum. Immunol. 71 (7) :727-730 (2010)

Background Reference 02

Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19 (5) :1356-1361 (2010)

Background Reference 03

Vahlquist, A., et al. J. Invest. Dermatol. 130 (2) :438-443 (2010)

Background Reference 04

Agarwal, S., et al. Exp. Dermatol. 18 (11) :939-946 (2009)

Other Product Names

Arachidonate 12-lipoxygenase, 12R-type, 12R-LOX, 12R-lipoxygenase, 11311-, Epidermis-type lipoxygenase 12, ALOX12B

Tested Applications

WB, IHC-P, Flow

Physical Properties

Liquid

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