Ruplizumab (CD40LG) - Research Grade Biosimilar
Product Specifications
Background
Ruplizumab is a humanized monoclonal antibody used as an immunosuppressive drug and is a component of Antova.Ruplizumab is an anti-CD40L monoclonal antibody.The binding of CD40 to its ligand, CD40L is a critical element in T cell activation.In systemic lupus erythematosus, CD40L is over-expressed on T cells, B cells and monocytes.
Immunogen
Humanized / CD40LG [Homo sapiens]
Clonality
Recombinant Monoclonal
Conjugation
Unconjugated
Type
Primary Antibodies, Biosimilars
Source
CHO cells
Field of Research
Neuroscience
Purification
>95%
Concentration
Batch dependent
Buffer
PBS buffer pH7.5
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 ˚ C for 1-2 weeks. Store at -20 ˚ C for 12 months. Store at -80 ˚ C for long term storage.
Fragment
IgG1-kappa
NCBI Organism
Homo sapiens
Other Product Names
BG-9588, hu5c8, CD40LG, CD40LG
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