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SARS-CoV-2 (COVID-19) Spike G142D Δ143-145VYY Antibody (Omicron)

Product Specifications

Background

SARS-CoV-2 Omicron variant, a variant of concern (VOC), known as B.1.1.529, was detected in South Africa at the end of November in 2021. However, it rapidly spread all over of the world and now it is the dominant variant in the world, which account for more than 90% of the new cases. Omicron variant spike protein carries around 30 amino acid changes, including mutations, deletions and insertions, 15 of which are in the receptor binding domain (RBD) . Enhanced transmission of the Omicron variant was observed globally, which is at least 70 times more contagious than the other variants. The Omicron variant affects the effectiveness of COVID-19 vaccine and is resistant to neutralization (monoclonal antibody treatments) to a large extent.

NCBI Gene ID

43740568

Swiss Prot

P0DTC2

Accession Number

QHD43416

Host

Rabbit

Reactivity

Virus

Immunogen

9793

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Infectious Disease, COVID-19

Purification

Anti-SARS-CoV-2 Omicron Variant Spike antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Homology

Predicted reactivity based on immunogen sequence: SARS-CoV Spike proteins: (33.3%)

Buffer

Anti-SARS-CoV-2 Omicron Variant Spike antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

SARS-CoV-2 Omicron Variant Spike antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=9793

Fragment

IgG

Specificity

It can only detect SARS-CoV-2 Omicron Variant (B.1.1.529) Spike protein and does not cross-react with the spike proteins of other variants.

Symbol

S

NCBI Official Name

Surface glycoprotein

NCBI Organism

Severe acute respiratory syndrome coronavirus 2

Background Reference 01

Gowrisankar et al. European Physical Journal Plus, 2022, 137 (1), 100.

Background Reference 02

Zhang et al. PNAS of U.S.A. 2021, 118 (47) :e2109905118.

Background Reference 03

Cameroni et al. Nature 2021.

Background Reference 04

Rossler et al. NEJM 2022.

Background Reference 05

Muik et al. Science 2022.

Other Product Names

SARS-CoV-2 Omicron Variant Spike antibody: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Surface Glycoprotein, Spike protein, Omicron Variant

Tested Applications

ELISA, WB, ICC, IF

Protein ID

1791269090

Physical Properties

Liquid

Available Sizes

Curated Selection

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