PEX3 (IN) Antibody

Product Specifications

Background

PEX3 Antibody: PEX3 is involved in peroxisome biosynthesis and integrity. It assembles membrane vesicles before the matrix proteins are translocated. As a docking factor for PEX19, PEX3 is necessary for the import of peroxisomal membrane proteins in the peroxisomes. Thus within the cell, PEX3 is stabilized by PEX19 preventing PEX3 aggregation. Mutations in the PEX19-binding domain of PEX3 reduce the affinity for PEX19 and destabilize PEX3.

NCBI Gene ID

8504

Swiss Prot

P56589

Accession Number

P56589

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

9667

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

PEX3 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1203 – A549 Cell Lysate

Concentration

1 mg/mL

Homology

Predicted species reactivity based on immunogen sequence: monkey (100%), cow (100%), chicken (100%)

Buffer

PEX3 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

PEX3 antibody can be stored at 4˚ C up to one year. Antibodies should not be exposed to prolonged high temperatures.

Fragment

IgG

Applications Notes

WB: 2 μ g/mL; IF: 20 μ g/mL. Antibody validated: Western Blot in human, mouse and rat samples; Immunofluorescence in human, mouse and rat samples. All other applications and species not yet tested.

Isoform

Human PEX3 has 1 isoform, (373aa, 42kD) . Mouse PEX3 has 1 isoform (372aa, 42kD) . Rat PEX3 has one isoform (372aa, 42kD) . 9667 can detect PEX3 in human, mouse and rat.

Symbol

PEX3

Positive Control 2

Cat. No. 17-003 – A549 Cell Slide

NCBI Organism

Homo sapiens

Background Reference 01

Ghaedi et al. Mol Biol Cell. 2000; 11 (6) :2085-2102

Background Reference 02

Fang et al. J Cell Biol. 2004;164 (6) :863-875

Background Reference 03

Hattula et al. PloS One. 2014; 9 (7) :e103101

Background Reference 04

Schmidt et al. Traffic. 2012; 13 (9) :1244-1260

Other Product Names

PEX3 Antibody: Peroxisomal biogenesis factor 3, Peroxin-3, Peroxisomal assembly protein PEX3

Tested Applications

ELISA, WB, IF

Protein ID

3914303

Physical Properties

Liquid

Available Sizes

Curated Selection

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