FZD6 (IN) Antibody

Product Specifications

Background

FZD6 Antibody: FZD6 acts as a receptor for Wnt proteins. Frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Together with FZD3, FZD6 is involved with neural tube closure and plays a role in the regulation of planar cell polarity, particularly in the orientation of asymmetric bundles of stereocilia on apical faces of a subset of sensory cells located in the inner ear.

NCBI Gene ID

8323

Swiss Prot

O60353

Accession Number

O60353

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

9551

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction, Stem Cell, Growth Factors

Purification

FZD6 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1219 - MCF-7 Cell Lysate

Concentration

1 mg/mL

Homology

Predicted species reactivity based on immunogen sequence: Chimpanzee (100%) ; Monkey (100%) ; Dog (100%)

Buffer

FZD6 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

FZD6 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Fragment

IgG

Isoform

Human FZD6 has 2 isoforms, including isoform 1 (706aa, 79.3kD) and isoform 2 (674aa, 75.6kD) . Mouse FZD6 has 1 isoform (709aa, 79kD) . Rat FZD6 has one isoform (710aa, 79.1kD) . 9551 can detect FZD6 in human, mouse and rat.