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SARS-CoV-2 (COVID-19) NSP13 (Helicase) Antibody

Product Specifications

Background

Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1) . The disease is the cause of the 2019–20 coronavirus outbreak (2) . The structure of 2019-nCoV consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. NSP13 is a multi-functional protein with a zinc-binding domain in N-terminus displaying RNA and DNA duplex-unwinding activities with 5' to 3' polarity. Activity of Helicase is dependent on magnesium (3,4) .

NCBI Gene ID

43740578

Swiss Prot

P0DTC1

Accession Number

YP_009725308.1

Host

Rabbit

Reactivity

Virus

Immunogen

9181

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Infectious Disease, COVID-19

Purification

SARS-CoV-2 (COVID-19) NSP13 (Helicase) Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Homology

Predicted reactivity based on immunogen sequence: SARS-CoV NSP13 (Helicase) protein: (80%)

Buffer

SARS-CoV-2 (COVID-19) NSP13 (Helicase) Antibody is supplied in PBS containing 0.02% sodium azide.

Shipping Conditions

Blue Ice

Storage Conditions

SARS-CoV-2 (COVID-19) NSP13 (Helicase) antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=9181

Fragment

IgG

Symbol

HEL

NCBI Official Name

ORF1a polyprotein; ORF1ab polyprotein

NCBI Organism

Severe acute respiratory syndrome coronavirus 2

Background Reference 01

Gorbalenya. bioRxiv: 2020.

Background Reference 02

Hui et al. Int J Infect Dis. 2020;91:264-266.

Background Reference 03

Tanner et. al. J.Biol. Chem. 2003;278:39578-39582

Other Product Names

Helicase, Non-structural protein 13, NSP13

Tested Applications

ELISA, IHC

Protein ID

1802476816

Physical Properties

Liquid

Available Sizes

Curated Selection

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