SARS-CoV-2 (COVID-19) NSP10 Antibody

Product Specifications

Background

Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1) . The disease is the cause of the 2019–20 coronavirus outbreak (2) . The structure of 2019-nCoV consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. NSP10 plays a pivotal role in viral transcription by stimulating both nsp14 3'-5' exoribonuclease and nsp16 2'-O-methyltransferase activities. Therefore it plays an essential role in viral mRNAs cap methylation (3) .

NCBI Gene ID

43740578

Swiss Prot

P0DTC1

Accession Number

YP_009742617.1

Host

Rabbit

Reactivity

Virus

Immunogen

9179

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Infectious Disease, COVID-19

Purification

SARS-CoV-2 (COVID-19) NSP10 Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Homology

Predicted reactivity based on immunogen sequence: SARS-CoV NSP10 protein: (80%)

Buffer

SARS-CoV-2 (COVID-19) NSP10 Antibody is supplied in PBS containing 0.02% sodium azide.

Shipping Conditions

Blue Ice

Storage Conditions

SARS-CoV-2 (COVID-19) NSP10 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Fragment

IgG

Symbol

Non-structural protein 10

NCBI Official Name

ORF1a polyprotein; ORF1ab polyprotein

NCBI Organism

Severe acute respiratory syndrome coronavirus 2

Background Reference 01

Gorbalenya. bioRxiv: 2020.

Background Reference 02

Hui et al. Int J Infect Dis. 2020;91:264-266.

Background Reference 03

Bouvet et. al. Proc. Natl. Acad. Sci. U.S.A. 2012;109:9372-9377

Other Product Names

NSP10, Growth factor-like peptide, GFL

Tested Applications

ELISA, WB, IHC

Protein ID

1826688927

Physical Properties

Liquid

Available Sizes

Curated Selection

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