SARS-CoV-2 (COVID-19) NSP6 Antibody

Product Specifications

Background

Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1) . The disease is the cause of the 2019–20 coronavirus outbreak (2) . The structure of 2019-nCoV consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. NSP6 plays a role in the initial induction of autophagosomes from host reticulum endoplasmic. Later, it limits the expansion of these phagosomes that are no longer able to deliver viral components to lysosomes (3,4) .

NCBI Gene ID

43740578

Swiss Prot

P0DTC1

Accession Number

YP_009742613.1

Host

Rabbit

Reactivity

Virus

Immunogen

9177

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Infectious Disease, COVID-19

Purification

SARS-CoV-2 (COVID-19) NSP6 Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Homology

Predicted reactivity based on immunogen sequence: SARS-CoV NSP6 protein: (94%)

Buffer

SARS-CoV-2 (COVID-19) NSP6 Antibody is supplied in PBS containing 0.02% sodium azide.

Shipping Conditions

Blue Ice

Storage Conditions

SARS-CoV-2 (COVID-19) NSP6 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Fragment

IgG

Applications Notes

Antibody validated: SARS-CoV-2 (COVID-19) NSP6 antibody can detect 2ng of free peptide at 1 μ g/mL in ELISA.

Symbol

Non-structural protein 6

NCBI Official Name

ORF1a polyprotein; ORF1ab polyprotein

NCBI Organism

Severe acute respiratory syndrome coronavirus 2

Background Reference 01

Gorbalenya. bioRxiv: 2020.

Background Reference 02

Hui et al. Int J Infect Dis. 2020;91:264-266.

Background Reference 03

Angelini et. al. DNA Cell Biol. 33:122-127 (2014)

Background Reference 04

Cottam et. al. Autophagy 2014; 10:1426-1441

Other Product Names

NSP6

Tested Applications

ELISA

Protein ID

1826688923

Physical Properties

Liquid

Available Sizes

Curated Selection

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