SARS-CoV-2 (COVID-19) Envelope Antibody

Product Specifications

Background

Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1) . The disease is the cause of the 2019–20 coronavirus outbreak (2) . The structure of 2019-nCoV consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. The envelope protein is a small polypeptide that contains at least one α-helical transmembrane domain. It involves in several aspects of the virus's life cycle, such as assembly, budding, envelope formation, and pathogenesis. E protein has membrane permeabilizing activity, which provides a possible rationale to inhibit in vitro ion channel activity of some synthetic corona virus E proteins, and also viral replication (3) .

NCBI Gene ID

43740570

Swiss Prot

QHD43418

Accession Number

QHD43418

Host

Rabbit

Reactivity

Virus

Immunogen

9169

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Infectious Disease, COVID-19

Purification

SARS-CoV-2 (COVID-19) Envelope Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Homology

Predicted reactivity based on immunogen sequence: SARS-CoV Envelope proteins: (93%)

Buffer

SARS-CoV-2 (COVID-19) Envelope Antibody is supplied in PBS containing 0.02% sodium azide.

Shipping Conditions

Blue Ice

Storage Conditions

SARS-CoV-2 (COVID-19) Envelope antibody can be stored at 4˚ C up to one year. Antibodies should not be exposed to prolonged high temperatures.

Fragment

IgG

Symbol

NCBI Official Name

Envelope protein

NCBI Organism

Wuhan seafood market pneumonia virus

Background Reference 01

Gorbalenya. bioRxiv: 2020.

Background Reference 02

Hui et al. Int J Infect Dis. 2020;91:264-266.

Background Reference 03

Pervushin et al. PLoS Pathog. 2009; 5 (7) : e1000511.

Other Product Names

SARS-CoV-2 (COVID-19, 2019-nCoV) Envelope Antibody: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Envelope protein, E protein

Tested Applications

ELISA, WB, IHC

Protein ID

1791269092

Physical Properties

Liquid

Available Sizes

Curated Selection

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