Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

HOOK3 Antibody

Product Specifications

Background

The HOOK proteins (HOOK1, HOOK2 and HOOK3) comprise a family of cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules mediating the spatial organization of diverse membrane-trafficking systems; their more divergent C-terminal domains mediate binding to organelles (1,2) . HOOK3 exists as a homodimer and participates in defining the architecture and localization of the Golgi complex through its central coiled-coil domain (3) . HOOK3 may regulate clearance of endocytosed receptors such as MSR1 (3,4) .

NCBI Gene ID

84376

Swiss Prot

Q86VS8

Accession Number

NP_115786

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Homeostasis

Purification

HOOK3 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1463 - Rat Brain Tissue Lysate

Concentration

1 mg/mL

Buffer

HOOK3 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

HOOK3 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=8425

Fragment

IgG

Specificity

HOOK3 antibody is human, mouse and rat reactive. HOOK3 antibody is predicted to not cross-react with HOOK1 and HOOK2.

Symbol

HOOK3

NCBI Official Name

Hook microtubule-tethering protein 3

NCBI Organism

Homo sapiens

Background Reference 01

Walenta JH, Didier AJ, Liu X, et al. The Golgi-associated hook3 protein is a member of a novel family of microtubule-binding proteins. J. Cell Biol. 2001; 152:923-34.

Background Reference 02

Sano H, Ishino M, Krämer H, et al. The microtubule-binding protein Hook3 interacts with a cytoplasmic domain of scavenger receptor A. J. Biol. Chem. 2007; 282:7973-81.

Background Reference 03

Herrmann L, Wiegmann C, Arsalan-Werner A, et al. Hook proteins: association with Alzheimer pathology and regulatory role of hook3 in amyloid beta generation. PLoS One 2015; 10:e0119423.

Background Reference 04

Ciampi R, Giordano TJ, Wikenheiser-Brokamp K, et al. HOOK3-RET: a novel type of RET/PTC rearrangement in papillary thyroid carcinoma. Endocr. Relat. Cancer 2007; 14:445-52.

Other Product Names

Hook microtubule-tethering protein 3, HK3, h-hook3, hHK3, FLJ31058, Protein Hook homolog 3

Tested Applications

ELISA, WB, IHC-P, IF

Protein ID

14165274

Physical Properties

Liquid

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

PTP1B (PTPN1) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI2G3]
TA503188BM 100 µL

PTP1B (PTPN1) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI2G3]

Ask
View Details
PRR13 antibody - middle region
MBS3213258-01 0.1 mL

PRR13 antibody - middle region

Ask
View Details
PRR13 antibody - middle region
MBS3213258-02 5x 0.1 mL

PRR13 antibody - middle region

Ask
View Details
Resmetirom (Mgl-3196) Impurity 35
RM-M468008-01 10 mg

Resmetirom (Mgl-3196) Impurity 35

Ask
View Details
Resmetirom (Mgl-3196) Impurity 35
RM-M468008-02 25 mg

Resmetirom (Mgl-3196) Impurity 35

Ask
View Details
Resmetirom (Mgl-3196) Impurity 35
RM-M468008-03 50 mg

Resmetirom (Mgl-3196) Impurity 35

Ask
View Details