CHADL Antibody

Product Specifications

Background

The Chondroadherin-like (CHADL) protein, also known as SLRR4B, is homologous to the Chondroadherin protein and is expressed cartillaginous tissues (1) . Like Chondroadherin, CHADL belongs to the small leucine-rich proteoglycan (SLRP) family and class IV subfamily and plays a significant role in the regulation of chondrocyte growth and proliferation (1,2) . CHADL is thought to play a negative regualtory role in collagen fibrillogenesis and chondrocyte differentiation (1) .

NCBI Gene ID

150356

Swiss Prot

Q6NUI6

Accession Number

NP_612490

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Stem Cell, Homeostasis

Purification

CHADL Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1467 - Rat Skeletal Muscle Tissue Lysate

Concentration

1 mg/mL

Buffer

CHADL Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

CHADL antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

Fragment

IgG

Specificity

CHADL antibody is human, mouse and rat reactive. CHADL antibody is predicted to not cross-react with Chondroadherin protein.

Symbol

CHADL

NCBI Official Name

Chondroadherin-like

NCBI Organism

Homo sapiens

Background Reference 01

Tillgren V, Ho JC, Onnerfjord P, et al. The novel small leucine-rich protein chondroadherin-like (CHADL) is expressed in cartilage and modulates chondrocyte differentitation. J. Biol. Chem. 2015; 290:918-25.

Background Reference 02

Neame PJ, Sommarin Y, Boynton RE, et al. The structure of a 38-kDa leucine-rich protein (chondroadherin) isolated from bovine cartilage. J. Biol. Chem. 1994; 269:21547-54.