TENM3 Antibody

Product Specifications

Background

The teneurin transmembrane protein 3 (TENM3) is a member of a family of four neuronal cell surface proteins homologous to the Drosophila pair-rule gene Ten-m (1,2) . TENM3 is expressed in cartilaginous cells during postnatal growth in mice (3), as well as the adult eye and optic stalk (4) . Homozygous null mutations in TENM3 causes microphthalmia in humans (5) .

NCBI Gene ID

55714

Swiss Prot

Q9P273

Accession Number

NP_001073946

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Stem Cell, Neuroscience

Purification

TENM3 antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1210 - HEK293 Cell Lysate

Concentration

1 mg/mL

Buffer

TENM3 antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

TENM3 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

Fragment

IgG

Specificity

TENM3 antibody is human, mouse and rat reactive. TENM3 antibody is predicted to not cross-react with other members of the TENM family.

Symbol

TENM3

NCBI Official Name

Teneurin transmembrane protein 3

NCBI Organism

Homo sapiens

Background Reference 01

Ben-Zur T and Wides R. Mapping homologs of Drosophila odd oz (odz) : Doc4/Odz to mouse chromosome 7, Odz1 to mouse chromosome 11; and ODZ3 to human chromosome Xq25. Genomics 1999; 58:102-3.

Background Reference 02

Rubin BP, Tucker RP, Martin D, et al. Tenurins: a novel family of neuronal cell surface proteins in vertebrates, homologous to the Drosophila pair-rule gene Ten-m. Dev. Biol. 1999; 216:195-209.

Background Reference 03

Murakami T, Fukunaga T, Takeshita N, et al. Expression of Ten-m/Odz3 in the fibrous layer of madibular condylar cartilage during postnatal growth in mice. J. Anat. 2010; 217:236-44.

Background Reference 04

Ben-Zur T, Feige E, Motro B, et al. The mammalian Odz gene family: homologs of a Drosophila pair-rule gene with expression implying distinct yet overlapping developmental roles. Dev. Biol. 2000; 217:107-20.