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SLC29A4 Antibody

Product Specifications

Background

SLC29A4 is a member of the equilibrative nucleoside transporter family which plays a key role in nucleoside and nucleobase uptake for salvage pathways of nucleotide synthesis (1,2) . SLC29A4 is a transmembrane protein that catalyzes the reuptake of monoamines into presynaptic neurons, thus determining the intensity and duration of monoamine neural signaling (1,3) . SLC29A4 has been shown to transport several compounds, including serotonin, dopamine, and the neurotoxin 1-methyl-4-phenylpyridinium (3) .

NCBI Gene ID

222962

Swiss Prot

Q7RTT9

Accession Number

NP_001035751

Host

Rabbit

Reactivity

Human

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Neuroscience

Purification

SLC29A4 antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1220 - SK-N-SH Cell Lysate

Concentration

1 mg/mL

Homology

Predicted species reactivity based on immunogen sequence: Mouse: (94%)

Buffer

SLC29A4 antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

SLC29A4 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=8131

Fragment

IgG

Specificity

SLC29A4 antibody is human specific. SLC29A4 antibody is predicted to not cross-react with other SLC29 proteins.

Symbol

SLC29A4

Positive Control 2

Cat. No. 10-301 - Human Brain Tissue Slide

NCBI Official Name

Solute carrier family 29 (equilibrative nucleoside transporter), member 4

NCBI Organism

Homo sapiens

Background Reference 01

Engel K, Zhou M, and Wang J. Identification and characterization of a novel monomine transporter in the human brain. J. Biol. Chem. 2004; 279:50042-9.

Background Reference 02

Young JD, Yao SY, Baldwin JM, et al. The human concentrative and equilibrative nucleoside transporter families, SLC28 and SLC29. Mol. Aspects. Med. 34:529-47.

Background Reference 03

Duan H and Wang J. Selective transport of monoamine neurotransmitters by human plasma membrane monoamine transporter and organic cation transporter 3. J. Pharmacol. Exp. Ther. 2010; 335:743-53.

Other Product Names

Solute carrier family 29 member 4, Equilibrative nucleoside transporter 4, ENT4, PMAT

Tested Applications

ELISA, WB, IHC-P, IF

Protein ID

100913034

Physical Properties

Liquid

Available Sizes

Curated Selection

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